• Themes:
 Myopathies, chronic diseases, dystrophies, muscle differentiation, muscle remodeling

.......................

•  General description:

By developing a synergy between basic and clinical research, this INSERM unit U 1046 " Physiology & Experimental Medicine :Cardiac and Skeletal Muscle" aims to study the pathophysiological mechanisms in skeletal and heart striated muscle but also in visceral and vascular smooth muscles. Then the study of associated diseases allows to develop therapeutic strategies for repairing and regeneration of these muscles.

The general theme of the team is presented in detail in our structure which is a Multi-team and comes in 4 Teams as follows:

The unit U1046 is represented by  4   Teams
  ......................................................................................

Team# I :

« Ions channels and calcium homeostasis in cardiac and vascular muscles»

Leader’s Name : Sylvain RICHARD  

Tel. : 04 67 41 52 41

E-mail : Richard

Keywords: calcium, contraction rate, ionic currents, signal transduction, heart, blood vessels.

Details on Team # I

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Team # II :

« Calcium signaling and sarcomeric function in cardiac and skeletal muscles»

Leader’s Name : Alain LACAMPAGNE

Tel. : 04 67 41 52 44

E-mail : Lacampagne

Keywords: Calcium, contraction, sarcomere, ionic currents, signal transduction, heart, skeletal striated muscles.

Details on Team # II

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Team # III :

« Skeletal muscle defects in acquired and inherited diseases»

Leader’s Name : Jacques MERCIER  

Tel. : 06 77 96 66 90

E-mail : Mercier

Keywords: Accumulation of intramuscular lipids, mitochondria, transporters, signaling pathways, inflammation, oxidative stress, nutrition, exercise.

Details on Team # III

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  Team # IV:

« Development of visceral smooth muscle cells and associated diseases »

Leader’s Name : Pascal DE SANTA BARBARA

Tel. : 04 67 41 52 34

E-mail : De Santa Barbara

Keywords: Intestinal motility, visceral smooth muscle, enteric nervous system; Pseudo chronic intestinal obstruction (PCIO), development of the digestive tract; signaling pathway; animal model

Details on Team # IV

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  Partnerships & Business Reference:

Pharmaceutical Industry: : SERVIER, CHIESI

External Collaborations:
  
  

Scientific Cooperation in FRANCE

(Montpellier)

Institut des NeurosciencesINM

INSERM U1054, Centre de Biochimie Structurale de Montpellier, INSERM U1054,CBS

Ecole Normale Supérieure de Chimie de Montpellier lENSCM

Centre de Biochimie MacromoléculaireCRBM

Institut d'Electronique du Sud ; Micro Rhéo AcoustiqueMIRA

Institut d'Electronique du Sud UMR5214

(National)

C entre de recherches du Service de Santé des ArméesLa TroncheCRSSA

CNRS-Marseille-Parc Scientifique de LuminyMarseilleUMR 6545

Laboratoire de Neurobiologie de l'Apprentissage de la Mémoire et de la CommunicationOrsay UMR 8620

La Clinique du SoufleOsséjaLa Solane

Laboratoire de Physiopathologie Cellulaire et Moléculaire de la RétineParis INSERM U 592

Institut Cochin,ParisINSERM U 567

CNRS-Université Paris-Sud 11 Institut de Cancérologie Gustave-RoussyVillejuif UMR 8126

(ABROAD)

Faculty of medicine, Masaryk University, Brno, Czech Republic  Department of Biology, 

Institute of Anatomy, Kiel,Allemagne. ICAU

University College London Institute of Child Health (Londres)AngleterreICH

Laboratoire de Neurobiologie, Université libre de Bruxelles, BelgiqueULB.

Université de Mons Hainaut Bruxelle; Laboratoire de Biologie MoléculaireBelgiqueUMH

Centre de Pneumologie Hopital Laval (Quebec)Canada HL

Université de Pavie Department of Neurological SciencesItalieUSP

Genome Institute of Singapore, République de Singapour GIS

Harvard Medical School Children's Hospital (Boston)USA CH

Université de Californie Berkeley; Department of Integrative BiologyUSADIB

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• Recent publications with (Impact Factor):  

Year 2013

1. Validation of High-Resolution DNA melting analysis for mutation scanning of the CDKL5 gene: Identification of novel mutations. Raymond L, Diebold B, Leroux C, Maurey H, Drouin-Garraud V, Delahaye A, Dulac O, Metreau J, Melikishvili G, Toutain A, Rivier F, Bahi-Buisson N, Bienvenu T.  Gene. 2013 Jan 1; 512(1):70-5. (IF =2.44).
2. Physical restraint in mechanically ventilated ICU patients: a survey of French practice. De Jonghe B, Constantin JM, Chanques G, Capdevila X, Lefrant JY, Outin H, Mantz J; The Group Interfaces Sédation. Intensive Care Med. 2013 Jan;39(1):31-37, (IF = 5.39).
3. Hemoperitoneum semiquantitative analysis on admission of blunt trauma patients improves the prediction of massive transfusion. Charbit J, Mahul M, Roustan JP, Latry P, Millet I, Taourel P, Capdevila X. Am J Emerg Med. Am J Emerg Med. 2013 Jan;31(1):130-6. (IF = 1.97).
4. STIM1 and Orai in cardiac hypertrophy and vascular proliferative diseases. Anne-Marie Lompre, Ludovic Benard, Youakim Saliba, Fleur Aubart, Jeremy Fauconnier, Jean-Sebastien Hulot. Front Biosci (Schol Ed). 2013 Jan 1;5:766-73. (IF=1.54).
5. Development and Validation of a Perioperative Satisfaction Questionnaire in Regional Anesthesia. Maurice-Szamburski A, Bruder N, Loundou A, Capdevila X, Auquier P. Anesthesiology. 2013 Jan;118(1):78-87. (IF =5.36).
6. As you tend to Tristan, don't ignore Iseult*. Chanques G, Hall JB. Crit Care Med. 2013 Jan;41(1):339-40. (IF = 6.48).
7. 6 cmH(2) O continuous positive airway pressure versus conventional oxygen therapy in severe viral bronchiolitis: A randomized trial. Milési C, Matecki S, Jaber S, Mura T, Jacquot A, Pidoux O, Chautemps N, Novais AR, Combes C, Picaud JC, Cambonie G. Pediatr Pulmonol. 2013 Jan;48(1):45-51 (IF=2,24).
8. High expression of the RNA-Binding Protein RBPMS2 in gastrointestinal stromal tumors. Hapkova I, Skarda J, Rouleau C, Thys A, Notarnicola C, Janikova M, Bernex F, Rypka M, Vanderwinden JM, Faure S, Vesely J, de Santa Barbara P. Exp Mol Pathol. 2013 Apr;94(2):314-21., (IF = 2.47).
9. Infectious chest complications in haematological malignancies. Bommart S, Bourdin A, Makinson A, Durand G, Micheau A, Monnin-Bares V, Klein F, Kovacsik H. Diagn Interv Imaging. 2013 Jan 9.In Press, (IF = 1.10).
10. Acute liver failure and elevated troponin-I: controversial results and significance? Jaber S, Paugam-Burtz C. Crit Care. 2013 Jan 14;17(1):102-103. (IF =4.61).
11. Testosterone secretion in elite adolescent swimmers does not modify bone mass acquisition: a 1-year follow-up study. Maïmoun L, Coste O, Philibert P, Briot K, Mura T, Galtier F, Castes-de-Paulet B, Mariano-Goulart D, Sultan C, Paris F. Fertil Steril. 2013 Jan;99(1):270-8. (IF=3.96).
12. Alzheimer's Disease Related Markers, Cellular Toxicity and Behavioral Deficits Induced Six Weeks after Oligomeric Amyloid-β Peptide Injection in Rats. Zussy C, Brureau A, Keller E, Marchal S, Blayo C, Delair B, Ixart G, Maurice T, Givalois L. PLoS One. 2013;8(1):e53117.(IF=4.53).
13. Acute Kidney Injury in the Critically Ill: Is Iodinated Contrast Medium Really Harmful? Ehrmann S, Badin J, Savath L, Pajot O, Garot D, Pham T, Capdevila X, Perrotin D, Lakhal K. Crit Care Med. 2013 Apr;41(4):1017-26. (IF=6.48).
14. Differences in Transcription Patterns between Induced Pluripotent Stem Cells Produced from the Same Germ Layer Are Erased upon Differentiation. Pirozhkova I, Barat A, Dmitriev P, Kim E, Robert T, Guégan J, Bilhou-Nabera C, Busato F, Tost J, Carnac G, Laoudj-Chenivesse D, Lipinski M, Vassetzky Y. PLoS One. 2013;8(1):e53033. (IF=4.53).
15. Improvement in conformability of the latest generation of thoracic stent grafts. Canaud L, Cathala P, Joyeux F, Branchereau P, Marty-Ané C, Alric P. J Vasc Surg. 2013 Apr;57(4):1084-1089., (IF=3,72).
16.  [Management of glycemia: An audit in 66 ICUs.] Orban JC, Scarlatti A, Lefrant JY, Molinari N, Leone M, Jaber S, Constantin JM, Allaouchiche B, Ichai C. Ann Fr Anesth Reanim. 2013 Feb;32(2):84-8 (IF =0.83).
17. [Cerebral near-infrared spectroscopy (NIRS) in paediatric anaesthesia.] Raux O, Sola C, Macq C, Dadure C. Ann Fr Anesth Reanim. 2013 Jan;32(1):e49-53 (IF =0.83).
18. [Regional anesthesia for postoperative analgesia at home in children.] Dadure C, Macq C, Sola C, Raux O. Ann Fr Anesth Reanim. 2013 Jan;32(1):e17-20 (IF =0.83).
19. Early Identification of Patients at Risk for Difficult Intubation in ICU: Development and validation of the MACOCHA Score in a Multicenter Cohort Study. De Jong A, Molinari N, Terzi N, Mongardon N, Arnal JM, Guitton C, Allaouchiche B, Paugam-Burtz C, Constantin JM, Lefrant JY, Leone M, Papazian L, Asehnoune K, Maziers N, Azoulay E, Pradel G, Jung B, Jaber S; AzuRéa Network for the FridaRéa study group. Am J Respir Crit Care Med. 2013 Apr 15;187(8):832-9. (IF= 11.08).
20. Moderate and prolonged hypercapnic acidosis may protect against ventilator-induced diaphragmatic dysfunction in healthy piglet: an in vivo study. Jung B, Sebbane M, Le Goff C, Rossel N, Chanques G, Futier E, Constantin JM, Matecki S, Jaber S. Crit Care. 2013 Jan 24;17(1):R15. (IF =4.61).
21. DUX4 expression in FSHD muscle cells: how could such a rare protein cause a myopathy? Tassin A, Laoudj-Chenivesse D, Vanderplanck C, Barro M, Charron S, Ansseau E, Chen YW, Mercier J, Coppée F, Belayew A.  J Cell Mol Med. 2013 Jan;17(1):76-89. (IF = 4.48).
22. Exercise hemorheology: Classical data, recent findings and unresolved issues. Connes P, Simmonds MJ, Brun JF, Baskurt OK. Clin Hemorheol Microcirc. 2013;53(1-2):187-99. (IF = 3.39).
23. Type 2 ryanodine receptor: A novel therapeutic target in myocardial ischemia/reperfusion. Fauconnier J, Roberge S, Saint N, Lacampagne A. Pharmacol Ther. 2013 Jun;138(3):323-32., (IF=9.35).
24. Drug Interactions between Non-Steroidal Anti-Inflammatory Drugs And Cardiovascular Treatments (Except Anti-Agregant Therapy). Lattuca B, Khoueiry Z, Malclès G, Davy JM, Leclercq F. Antiinflamm Antiallergy Agents Med Chem. 2013;12: 36-46. (IF = in progress).
25. Pro- And Anti-Arrhythmic Effects of Anti-Inflammatory drugs. Granier M, Massin F, Pasquié JL. Antiinflamm Antiallergy Agents Med Chem. 2013; 12: 83-93 (IF = in progress).
26. Cardiovascular adverse effects of anti-inflammatory drugs. Roubille C, Martel-Pelletier J, Davy JM, Haraoui B, Pelletier JP. Antiinflamm Antiallergy Agents Med Chem. 2013; 12: 55-67, (IF =in progress).
27. Right coronary cusp perforation after mitral valve replacement.  Al Yamani MI, Frapier JM, Battistella PD, Albat B. Interact Cardiovasc Thorac Surg. 2013 Mar;16(3):387-8.
28. Neurally adjusted ventilator assist versus pressure support ventilation for noninvasive ventilation during acute respiratory failure: a cross-over physiological study. Bertrand PM, Futier E, Coisel Y, Matecki S, Jaber S, Constantin JM. Chest. 2013 Jan;143(1):30-6,  (IF = 6.51).
29. Sub-endocardial increase in ROS production affects regional contractile function in ischemic heart failure. Andre L, Fauconnier J, Reboul C, Feillet-Coudray C, Meschin P, Farah C, Fouret G, Richard S, Lacampagne A, Cazorla O. Antioxid Redox Signal. 2013 Mar 20;18(9):1009-20, (IF =8.45).
30. Hemi-aortic arch debranching for hybrid aortic arch repair by sequential transposition of the left common carotid and subclavian arteries. Canaud L, Joyeux F, Ziza V, Branchereau P, Marty-Ané C, Alric P. J Thorac Cardiovasc Surg. 2013 Mar;145(3):764-7 (IF = 3.61).
31. Arginine butyrate: a therapeutic candidate for Duchenne muscular dystrophy. Vianello S, Yu H, Voisin V, Haddad H, He X, Foutz AS, Sebrié C, Gillet B, Roulot M, Fougerousse F, Perronnet C, Vaillend C, Matecki S, Escolar D, Bossi L, Israël M, de la Porte S. FASEB J. 2013 Feb 21 in Press (IF = 5.71 ).
32. Noninvasive mechanical ventilation in patients having declined tracheal intubation. Azoulay E, Kouatchet A, Jaber S, Lambert J, Meziani F, Schmidt M, Schnell D, Mortaza S, Conseil M, Tchenio X, Herbecq P, Andrivet P, Guerot E, Lafabrie A, Perbet S, Camous L, Janssen-Langenstein R, Collet F, Messika J, Legriel S, Fabre X, Guisset O, Touati S, Kilani S, Alves M, Mercat A, Similowski T, Papazian L, Meert AP, Chevret S, Schlemmer B, Brochard L, Demoule A. Intensive Care Med. 2013 Feb;39(2):292-301. (IF =5.39).
33. Chest-wall reconstruction in case of infection of the operative site: is there any interest in titanium rib osteosynthesis? Berthet JP, Solovei L, Tiffet O, Gomez-Caro A, Bommart S, Canaud L, Alric P, Marty-Ané CH.  Eur J Cardiothorac Surg. 2013 Feb 27. In Press. (IF = 2,55).
34. Nutritional and metabolic determinants of blood rheology differ between trained and sedentary individuals. Varlet-Marie E, Guiraudou M, Fédou C, Raynaud de Mauverger E, Durand F, Brun JF. Clin Hemorheol Microcirc. 2013 Feb 27. In Press. (IF = 3.40).
35. Feasibility and effectiveness of prone position in morbidly obese ARDS patients: a case-control clinical study. De Jong A, Molinari N, Sebbane M, Prades A, Futier E, Jung B, Chanques G, Jaber S. Chest. 2013 Feb 28. In Press. (IF = 6.22).
36. Obesity-related increase in whole blood viscosity includes different profiles according to fat localization. Guiraudou M, Varlet-Marie E, Raynaud de Mauverger E, Brun JF. Clin Hemorheol Microcirc. 2013 Mar 1. In Press. (IF = 3.40).
37. Clara Cells and Injury Post Lung Transplantation: An Evolving Story. Bourdin A, Mifsud NA, Chanez B, Chanez P, Snell G, Kotsimbos TC. Am J Transplant. 2013 May;13(5):1370, (IF =6.39).
38. Exercise hemorheology: Moving from old simplistic paradigms to a more complex picture. Brun JF, Varlet-Marie E, Romain AJ, Guiraudou M, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2013 Mar 11. . In Press. (IF = 3.40).
39. Three-Dimensional High-Resolution Ultrasound-Guided Nerve Blocks: A New Panoramic Vision of Local Anesthetic Spread and Perineural Catheter Tip Location. Choquet O, Capdevila X. Anesth Analg. 2013 May;116(5):1176-81. (IF = 3.28).
40. Peripubertal female athletes in high-impact sports show improved bone mass acquisition and bone geometry. Maïmoun L, Coste O, Philibert P, Briot K, Mura T, Galtier F, Mariano-Goulart D, Paris F, Sultan C. Metabolism. 2013 Mar 11. In Press. (IF = 2.77).
41. Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Milési C, Baleine J, Matecki S, Durand S, Combes C, Novais AR, Combonie G. Intensive Care Med. 2013 Jun;39(6):1088-94. (avec la correction suivante : 2013 Jun;39(6):1170)  (IF = 5.39).
42. Traitement de faux anévrisme post-cathétérisme par injection percutanée échoguidée de thrombine : à propos de 30 cas. G. Böge, J.-P. Laroche, P. Alric   Journal des Maladies Vasculaires, 2013 Mar;38(2):112.  (IF = 0.54).
43. Prevalence, characteristics and prognosis role of type 1 ST elevation in the peripheral ECG leads in patients with Brugada syndrome. Rollin A, Sacher F, Gourraud JB, Pasquié JL, Raczka F, Duparc A, Mondoly P, Cardin C, Delay M, Chatel S, Derval N, Denis A, Sadron M, Davy JM, Hocini M, Jaïs P, Jesel L, Haïssaguerre M, Probst V, Maury P. Heart Rhythm. 2013 Mar 11 In Press, (IF =4.10).
44. Accuracy assessment of online glucose monitoring by a subcutaneous enzymatic glucose sensor during exercise in patients with type 1 diabetes treated by continuous subcutaneous insulin infusion. Radermecker RP, Fayolle C, Brun JF, Bringer J, Renard E. Diabetes Metab. 2013 Mar 19. In Press, (IF = 2.72).
45. Impact of tobacco and alcohol consumption in patients registered on waiting list on early morbidity following liver transplantation. Perney P, Segalas F, Nalpas B, Chanques G, Rigole H, Duny Y, Blanc F, Jaber S, Pageaux GP. Clin Res Hepatol Gastroenterol. 2013 Mar 19. In Press, (IF = 0.25).
46. Prescribing nonopioids in mechanically ventilated critically ill patients. Payen JF, Genty C, Mimoz O, Mantz J, Bosson JL, Chanques G. J Crit Care. 2013 Mar 19. In Press, (IF = 2.36).
47. Quercetin induces insulin secretion by direct activation of L- type calcium channels in the pancreatic β cells. Bardy G, Virsolvy A, Quignard J, Ravier M, Bertrand G, Dalle S, Cros G, Magous R, Richard S, Oiry C. Br J Pharmacol. 2013 Mar 27. In Press, (IF = 4.63).
48. 6 Weeks of Low Volume, Low Intensity Training Aggravate Pulmonary Diffusing Capacity in Highly Trained Athletes. Galy O, Maimoun L, Coste O, Manetta J, Boussana A, Préfaut C, Hue O. Int J Sports Physiol Perform. 2013 Mar 26. In Press, (IF = 1.97).
49. Blunted muscle angiogenic training-response in copd patients versus sedentary controls. Gouzi F, Préfaut C, Abdellaoui A, Roudier E, de Rigal P, Molinari N, Laoudj-Chenivesse D, Mercier J, Birot O, Hayot M. Eur Respir J. 2013 Apr;41(4):806-14 (IF =5.89).
50. Protective Mechanical Ventilation during General Anesthesia for Open Abdominal Surgery Improves Postoperative Pulmonary Function. Severgnini P, Selmo G, Lanza C, Chiesa A, Frigerio A, Bacuzzi A, Dionigi G, Novario R, Gregoretti C, de Abreu MG, Schultz MJ, Jaber S, Futier E, Chiaranda M, Pelosi P. Anesthesiology. 2013 Mar 29. In Press, (IF = 5.36).
51. Response.  (Acknowledgement to Dr Esquinas comments on previous reports in Chest 2013 143(1) 30-36). Futier E, Jaber S, Constantin JM. Chest. 2013 Apr 1;143(4):1181-2 . (IF = 6.22).
52. The pain, agitation, and delirium practice guidelines for adult critically ill patients: a post-publication perspective.  Skrobik Y, Chanques G. Ann Intensive Care. 2013 Apr 2;3(1):9.(IF= in progress).  
53. REFERENCE VALUES FOR VASTUS LATERALIS FIBER SIZE AND TYPE IN HEALTHY SUBJECTS OVER 40 YEARS OLD: A SYSTEMATIC REVIEW AND META-ANALYSIS. Gouzi F, Maury J, Molinari N, Pomiès P, Mercier J, Prefaut CG, Hayot M. J Appl Physiol. 2013 Apr 4.  In Press. (IF = 4.10).
54. Closed loop mechanical ventilation. Wysocki M, Jouvet P, Jaber S. J Clin Monit Comput. 2013 Apr 7 .  In Press. (IF =0.88).  
55. [Congenital myasthenic syndromes: difficulties in the diagnosis, course and prognosis, and therapy--The French National Congenital Myasthenic Syndrome Network experience]. Eymard B, Stojkovic T, Sternberg D, Richard P, Nicole S, Fournier E, Béhin A, Laforêt P, Servais L, Romero N, Fardeau M, Hantaï D; Membres du réseau national Syndromes Myasthéniques Congénitaux (18 collaborateurs dont Rivier F.)  Rev Neurol (Paris). 2013 Feb;169 Suppl 1:S45-55. (IF = 0.48).
56. Role of comorbid conditions in asthma hospitalizations in the south of France. Aubas C, Bourdin A, Aubas P, Gamez AS, Halimi L, Vachier I, Malafaye N, Chanez P, Molinari N. Allergy. 2013 May;68(5):637-643. (IF= 6.27).
57. Pre-interventional haemostatic assessment: Guidelines from the French Society of Anaesthesia and Intensive Care. Bonhomme F, Ajzenberg N, Schved JF, Molliex S, Samama CM; (+French Anaesthetic and Intensive Care Committee on Evaluation of Routine Preoperative Testing, Comité auquel participe  Christophe Dadure) .Eur J Anaesthesiol. 2013 Apr;30(4):142-62. (IF= 2.23).
58. Video-assisted thoracoscopic lobectomy: an unavoidable trend? A retrospective single-institution series of 410 cases. Marty-Ané CH, Canaud L, Solovei L, Alric P, Berthet JP. Interact Cardiovasc Thorac Surg. 2013 Apr 16. In Press, (IF= in progress).
59. Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes. Dmitriev P, Barat A, Polesskaya A, O Connell MJ, Robert T, Dessen P, Walsh TA, Lazar V, Turki A, Carnac G, Laoudj-Chenivesse D, Lipinski M, Vassetzky YS. BMC Genomics. 2013 Apr 18;14(1):265.(IF=4,07).
60. Decreasing severe pain and serious adverse events while moving intensive care unit patients: a prospective interventional study (the NURSE-DO project). de Jong A, Molinari N, de Lattre S, Gniadek C, Carr J, Conseil M, Susbielles MP, Jung B, Jaber S, Chanques G. Crit Care. 2013 Apr 18;17(2):R74.(IF=4.97).
61. Case report: three-dimensional high-resolution ultrasound-guided nerve blocks: a new panoramic vision of local anesthetic spread and perineural catheter tip location. Choquet O, Capdevila X.  Anesth Analg. 2013 May;116(5):1176-81.(IF = 3.28).
62. Prospective Randomized Crossover Study of a New Closed-loop Control System versus Pressure Support during Weaning from Mechanical Ventilation. Clavieras N, Wysocki M, Coisel Y, Galia F, Conseil M, Chanques G, Jung B, Arnal JM, Matecki S, Molinari N, Jaber S. Anesthesiology. 2013 Apr 24 In Press, (IF = 5.36).
63. Diaphragm Dysfunction on Admission to ICU: Prevalence, Risk Factors and Prognostic Impact - a Prospective Study. Demoule A, Jung B, Prodanovic H, Molinari N, Chanques G, Coirault C, Matecki S, Duguet A, Similowski T, Jaber S. Am J Respir Crit Care Med. 2013 May 3. In Press, (IF= 11.08).
64. Non-invasive ventilation for end-of-life oncology patients. Azoulay E, Kouatchet A, Jaber S, Meziani F, Papazian L, Brochard L, Demoule A. Lancet Oncol. 2013 May;14(6):e200-1. (IF=22.58)
65. Isoprostanes and Neuroprostanes: Total synthesis, biological activity and biomarkers of oxidative stress in humans. Galano JM, Mas E, Barden A, Mori TA, Signorini C, De Felice C, Barrett A, Opere C, Pinot E, Schwedhelm E, Benndorf R, Roy J, Le Guennec JY, Oger C, Durand T. Prostaglandins Other Lipid Mediat. 2013 May 2. In Press, (IF= 2.70).
66. Natural history of Barth syndrome: a national cohort study of 22 patients. Rigaud C, Lebre AS, Touraine R, Beaupain B, Ottolenghi C, Chabli A, Ansquer H, Ozsahin H, Di Filippo S, De Lonlay P, Borm B, Rivier F, Vaillant MC, Mathieu-Dramard M, Goldenberg A, Viot G, Charron P, Rio M, Bonnet D, Donadieu J. Orphanet J Rare Dis. 2013 May 8;8(1):70. (IF=5,07).
67. Specific bone mass acquisition in elite female athletes. Maïmoun L, Coste O, Mura T, Philibert P, Galtier F, Mariano-Goulart D, Paris F, Sultan C.  J Clin Endocrinol Metab. 2013 May 10.In Press, (IF=6.37).
68. Expanding the phenotype of IQSEC2 mutations: truncating mutations in severe intellectual disability. Tran Mau-Them F, Willems M, Albrecht B, Sanchez E, Puechberty J, Endele S, Schneider A, Ruiz Pallares N, Missirian C, Rivier F, Girard M, Holder M, Manouvrier S, Touitou I, Lefort G, Sarda P, Moncla A, Drunat S, Wieczorek D, Genevieve D. Eur J Hum Genet. 2013 May 15 In Press, (IF= 4.40).
69. Why Is Lightening Sedation in Critically Ill Patients So Difficult?* Chanques G, Jaber S.Crit Care Med. 2013 Jun;41(6):1573-1575.(IF=6.48).
70. [Ketamine, makes happy… Not always in children!]  Dadure C, Sola C. Ann Fr Anesth Reanim. 2013 May 14.In Press, (IF =0.83).
71. Prone Positioning in Severe Acute Respiratory Distress Syndrome. Guérin C, Reignier J, Richard JC, Beuret P, Gacouin A, Boulain T, Mercier E, Badet M, Mercat A, Baudin O, Clavel M, Chatellier D, Jaber S, Rosselli S, Mancebo J, Sirodot M, Hilbert G, Bengler C, Richecoeur J, Gainnier M, Bayle F, Bourdin G, Leray V, Girard R, Baboi L, Ayzac L; the PROSEVA Study Group, (=Avec la participation de B. Jung).  N Engl J Med. 2013 May 20. In Press, (IF = 53.30).

Year 2012

1. Grape Polyphenols Prevent Fructose-Induced Oxidative Stress and Insulin Resistance in First-Degree Relatives of Type 2 Diabetic Patients.Hokayem M, Blond E, Vidal H, Lambert K, Meugnier E, Feillet-Coudray C, Coudray C, Pesenti S, Luyton C, Lambert-Porcheron S, Sauvinet V, Fedou C, Brun JF, Rieusset J, Bisbal C, Sultan A, Mercier J, Goudable J, Dupuy AM, Cristol JP, Laville M, Avignon A. Diabetes Care. 2012 Dec 28. In Press, (IF =8.08).
2. FSHD Myotubes with Different Phenotypes Exhibit Distinct Proteomes. Tassin A, Leroy B, Laoudj-Chenivesse D, Wauters A, Vanderplanck C, Le Bihan MC, Coppée F, Wattiez R, Belayew A. PLoS One. 2012;7(12):e51865. (IF = 4.54).
3. Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms. Cheillan D, Curt MJ, Briand G, Salomons GS, Mention-Mulliez K, Dobbelaere D, Cuisset JM, Lion-François L, Portes VD, Chabli A, Valayannopoulos V, Benoist JF, Pinard JM, Simard G, Douay O, Deiva K, Afenjar A, Héron D, Rivier F, Chabrol B, Prieur F, Cartault F, Pitelet G, Goldenberg A, Bekri S, Gerard M, Delorme R, Tardieu M, Porchet N, Vianey-Saban C, Vamecq J. Orphanet J Rare Dis. 2012 Dec 13;7(1):96 (IF = 5.96).
4. Cytomegalovirus and herpes simplex virus effect on the prognosis of mechanically ventilated patients suspected to have ventilator-associated pneumonia. Coisel Y, Bousbia S, Forel JM, Hraiech S, Lascola B, Roch A, Zandotti C, Million M, Jaber S, Raoult D, Papazian L. PLoS One. 2012;7(12):e51340. (IF = 4.54).
5. Disruption of cyclophilin D-mediated calcium transfer from the ER to mitochondria contributes to hepatic ER stress and insulin resistance. Rieusset J, Fauconnier J, Paillard M, Belaidi E, Tubbs E, Chauvin MA, Durand A, Bravard A, Teixeira G, Bartosch B, Michelet M, Theurey P, Vial G, Demion M, Blond E, Zoulim F, Gomez L, Vidal H, Lacampagne A, Ovize M. Hepatology. 2012 Dec 5.In Press, (IF =11.66).
6. Pneumonia in immunocompromised patients: more than meets the eye. Signe J, Jung B, Nougaret S, Belafia F, Panaro F, Bismuth M, Jaber S. Am J Respir Crit Care Med. 2012 Dec 1;186(11):e18.  (IF =11.08).
7. [Cost-effectiveness of lung volume reduction coil treatment in emphysema. STIC REVOLENS]. Deslee G, Barbe C, Bourdin A, Durand-Zaleski I, Dutau H, Jolly D, Jounieaux V, Kessler R, Mal H, Pison C, Thiberville L, Vergnon JM, Marquette CH. Rev Mal Respir. 2012 Nov;29(9):1157-64. (IF = 0.58).
8. Lack of progressive arteriopathy and stroke recurrence among children with cryptogenic stroke. Darteyre S, Chabrier S, Presles E, Bonafé A, Roubertie A, Echenne B, Leboucq N, Rivier F. Neurology. 2012 Dec 11;79(24):2342-8. (IF =8.31).
9. Effects of etomidate on complications related to intubation and on mortality in septic shock patients treated with hydrocortisone: a propensity score analysis. Jung B, Clavieras N, Nougaret S, Molinari N, Roquilly A, Cisse M, Carr J, Chanques G, Asehnoune K, Jaber S. Crit Care. 2012 Nov 21;16(6):R224. (IF =4.97).
10. ANT-VDAC1 interaction is direct and depends on ANT isoform conformation in vitro. Allouche M, Pertuiset C, Robert JL, Martel C, Veneziano R, Henry C, El Dein OS, Saint N, Brenner C, Chopineau J. Biochem Biophys Res Commun. 2012 Dec 7;429(1-2):12-7, (IF =2.52).
11. Glutathione peroxidase 3, a new retinoid target gene, is critical for human skeletal muscle precursor cell survival.  Haddad ME, Jean E, Turki A, Hugon G, Vernus B, Bonnieu A, Passerieux E, Hamade A, Mercier J, Laoudj-Chenivesse D, Carnac G. J Cell Sci. 2012 Dec 15;125(Pt 24):6147-56,   (IF=6.40).
12. Adherence in severe asthma. Bourdin A, Halimi L, Vachier I, Paganin F, Lamouroux A, Gouitaa M, Vairon E, Godard P, Chanez P.Clin Exp Allergy. 2012 Nov;42(11):1566-74, (IF =5.03 ).
13. The Practice of Therapeutic Hypothermia after Cardiac Arrest in France: A National Survey. Orban JC, Cattet F, Lefrant JY, Leone M, Jaber S, Constantin JM, Allaouchiche B, Ichai C; for the AzuRéa group . PLoS One. 2012;7(9):e45284 (IF =4.54)
14. Variable compliance with clinical practice guidelines identified in a 1-day audit at 66 French adult intensive care units. Leone M, Ragonnet B, Alonso S, Allaouchiche B, Constantin JM, Jaber S, Martin C, Fabbro-Peray P, Lefrant JY; Azuréa Group. (avec Capdevila X, et Chanques G,   comme collaborateurs), Crit Care Med. 2012 Dec;40(12):3189-3195. (IF=6.45).
15. Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation. Picard M, Jung B, Liang F, Azuelos I, Hussain S, Goldberg P, Godin R, Danialou G, Chaturvedi R, Rygiel K, Matecki S, Jaber S, Des Rosiers C, Karpati G, Ferri L, Burelle Y, Turnbull DM, Taivassalo T, Petrof BJ. Am J Respir Crit Care Med. 2012 Dec 1;186(11):1140-9, (IF =11.08).
16. The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon on postoperative delirium in older patients undergoing hip fracture surgery.  Coburn M, Sanders RD, Maze M, Rossaint R, Belda J, Borghi B, Rosencher N, Arnold G, Albaladejo P, Capdevila X, Minville V, Kienbaum P, Mynard V, Chong CF, Kunitz O. Trials. 2012 Sep 27;13(1):180, (IF =2.63).
17. Zinc modulation of basal and β-adrenergically stimulated L-type Ca(2+) current in rat ventricular cardiomyocytes: consequences in cardiac diseases. Alvarez-Collazo J, Díaz-García CM, López-Medina AI, Vassort G, Alvarez JL. Pflugers Arch. 2012 Nov;464(5):459-70. (IF = 4.46).
18. Chest radiographs in 104 French ICUs: current prescription strategies and clinical value (the RadioDay study). Lakhal K, Serveaux-Delous M, Lefrant JY, Capdevila X, Jaber S; AzuRéa network for the RadioDay study group. Intensive Care Med. 2012 Nov;38(11):1787-99, (IF =5,40 ).
19. Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey. Selton-Suty C, Célard M, Le Moing V, Doco-Lecompte T, Chirouze C, Iung B, Strady C, Revest M, Vandenesch F, Bouvet A, Delahaye F, Alla F, Duval X, Hoen B; AEPEI Study Group. (Comprenant parmi les membres de ce groupe de travail: Chanques  G, Jung B, Frapier JM,).  Clin Infect Dis. 2012 May;54(9):1230-9. (IF = 9.15).
20. Natriuretic Peptide-Driven Fluid Management during Ventilator Weaning: A Randomized Controlled Trial. Mekontso Dessap A, Roche-Campo F, Kouatchet A, Tomicic V, Beduneau G, Sonneville R, Cabello B, Jaber S, Azoulay E, Castanares-Zapatero D, Devaquet J, Lellouche F, Katsahian S, Brochard L. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1256-63. (IF =11.08).
21. Endovascular Repair of a Left Common Carotid Pseudoaneurysm Associated With a Jugular-Carotid Fistula After Gunshot Wound to the Neck. Faure E, Canaud L, Marty-Ané C, Alric P. Ann Vasc Surg. 012 Nov;26(8):1129.e13-6. (IF = 1.23).
22. [How to easily and efficiently implement a quality improvement project regarding sedation-analgesia in Intensive care unit?] Chanques G, Jaber S. Ann Fr Anesth Reanim. 2012 Oct;31(10):767-9.,  (IF =0.83).
23. [Epidemiologic picture of one-year-pediatric anesthesia in France.] Macq C, Seguret F, Bringuier S, Sola C, Capdevila X, Dadure C. Ann Fr Anesth Reanim. 2012 Nov;31(11):835-9 (IF =0.83).
24. Immunologic therapeutic interventions in asthma: impact on natural history. Bourdin A, Humbert M, Chanez P. Clin Chest Med. 2012 Sep; 33(3):585-97 (IF = 3.28).
25. Physical Activity Targeted at Maximal Lipid Oxidation: A Meta-Analysis. Romain AJ, Carayol M, Desplan M, Fedou C, Ninot G, Mercier J, Avignon A, Brun JF. J Nutr Metab. 2012; 2012:285395. (IF = 2.88).
26. Age should be considered in the decision making of prophylactic splenic angioembolization in nonoperative management of blunt splenic trauma: A study of 208 consecutive civilian trauma patients. Brault-Noble G, Charbit J, Chardon P, Barral L, Guillon F, Taourel P, Capdevila X, Millet I. J Trauma Acute Care Surg. 2012 Nov;73(5):1213-20. (IF =    3.13).
27.  Local anesthetic 'in-situ' toxicity during peripheral nerve blocks: update on mechanisms and prevention. Nouette-Gaulain K, Capdevila X, Rossignol R. Curr Opin Anaesthesiol. 2012 Oct;25(5):589-95. (IF = 2.21).
28. Peroxisome proliferator-activated receptor coactivator 1- gene transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscle. Godin R, Daussin FN, Matecki S, Li T, Petrof BJ, Burelle Y. J Physiol. 2012 Nov 1;590(Pt 21):5487-502. (IF =4.93).
29. [Sfar research awards 2012.] Langeron O, Jaber S, Benhamou D, Plaud B. Ann Fr Anesth Reanim. 2012 Sep;31(9):671-2. (IF =0.83). 
30. Donor Clara Cell Secretory Protein Polymorphism is a Risk Factor for Bronchiolitis Obliterans Syndrome After Lung Transplantation. Bourdin A, Mifsud NA, Chanez B, McLean C, Chanez P, Snell G, Kotsimbos TC. Transplantation. 2012 Sep 27;94(6):652-658. , (IF = 4.00).
31. Preoxygenation in obese patient with non-invasive pressure support ventilation: Keep the pressure!] Constantin JM, Jaber S. Ann Fr Anesth Reanim. 2012 Sep;31(9):673-4, (IF = 0.88).
32. Could heart rate play a role in pericardial inflammation? Khoueiry Z, Roubille C, Nagot N, Lattuca B, Piot C, Leclercq F, Delseny D, Busseuil D, Gervasoni R, Davy JM, Pasquié JL, Cransac F, Sportouch-Dukhan C, Macia JC, Cung TT, Massin F, Cade S, Cristol JP, Barrère-Lemaire S, Roubille F. Med Hypotheses. 2012 Oct;79(4):512-5., (IF =  1.19).
33. Long-chain acylcarnitines regulate the HERG channel. Ferro F, Ouillé A, Tran TA, Fontanaud P, Bois P, Babuty D, Labarthe F, Le Guennec JY. PLoS One. 2012;7(7):e41686. (IF =4,54).
34.  [Can we perform an ultrasound-guided regional anesthesia in an anaesthetized patient?] Choquet O, Paqueron X, Capdevila  X.  Ann Fr Anesth Reanim. 2012 Sep;31(9):e187-91., (IF = 0.88).
35.  Where should the tip of the needle be located in ultrasound-guided peripheral nerve blocks? Choquet O, Morau D, Biboulet P, Capdevila X. Curr Opin Anaesthesiol. 2012 Oct;25(5):596-602. (IF =2.21).
36. Carbon Monoxide Induces Cardiac Arrhythmia via Induction of the Late Na+ Current. Dallas ML, Yang Z, Boyle JP, Boycott HE, Scragg JL, Milligan CJ, Elies J, Duke A, Thireau J, Reboul C, Richard S, Bernus O, Steele DS, Peers C. Am J Respir Crit Care Med. 2012 Oct 1;186(7):648-656, (IF = 11.08).
37. Consensus statement on the care of the hyperglycaemic/diabetic patient during and in the immediate follow-up of acute coronary syndrome. Vergès B, Avignon A, Bonnet F, Catargi B, Cattan S, Cosson E, Ducrocq G, Elbaz M, Fredenrich A, Gourdy P, Henry P, Lairez O, Leguerrier AM, Monpère C, Moulin P, Vergès-Patois B, Roussel R, Steg G, Valensi P; Diabetes and Cardiovascular Disease study group of the Société francophone du diabète (SFD); Société française de cardiologie (SFC). Arch Cardiovasc Dis. 2012 Apr;105(4):239-53. (IF= 1.51).
38. Functional muscle impairment in Facioscapulohumeral Muscular Dystrophy is correlated with oxidative stress and mitochondrial dysfunction. Turki A, Hayot M, Carnac G, Pillard F, Passerieux E, Bommart S, de Mauverger ER, Hugon G, Pincemail J, Pietri S, Lambert K, Belayew A, Vassetzky Y, Morales RJ, Mercier J, Laoudj-Chenivesse D. Free Radic Biol Med. 2012 Jul 11;53(5):1068-1079. (IF=5,77).
39. Voriconazole for chronic pulmonary aspergillosis: a prospective multicenter trial. Cadranel J, Philippe B, Hennequin C, Bergeron A, Bergot E, Bourdin A, Cottin V, Jeanfaivre T, Godet C, Pineau M, Germaud P. Eur J Clin Microbiol Infect Dis.  2012 Nov;31(11):3231-9, (IF =2.86).
40. Etomidate increases susceptibility to pneumonia in trauma patients. Asehnoune K, Mahe PJ, Seguin P, Jaber S, Jung B, Guitton C, Chatel-Josse N, Subileau A, Tellier AC, Masson F, Renard B, Malledant Y, Lejus C, Volteau C, Sébille V, Roquilly A. Intensive Care Med. 2012 Oct;38(10):1673-82. (IF =5,40).
41. Effect of a high dose of simvastatin on muscle mitochondrial metabolism and calcium signaling in healthy volunteers. Galtier F, Mura T, de Mauverger ER, Chevassus H, Farret A, Gagnol JP, Costa F, Dupuy A, Petit P, Cristol JP, Mercier J, Lacampagne A. Toxicol Appl Pharmacol. 2012 Sep 15; 263(3):281-6. (IF =4.45).
42. A haemoperitoneum does not indicate active bleeding in the peritoneum in 50% of hypotensive blunt trauma patients: A study of 110 severe trauma patients. Charbit J, Millet I, Lakhal K, Brault-Noble G, Guillon F, Taourel P, Capdevila X. Injury. 2012 Jul 4. In Press, (IF =2.34).
43. Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction. Mrozek S, Jung B, Petrof BJ, Pauly M, Roberge S, Lacampagne A, Cassan C, Thireau J, Molinari N, Futier E, Scheuermann V, Michel Constantin J, Matecki S, Jaber S. Anesthesiology. 2012 Sep;117(3):560-567. (IF =5.48)
44.  Does the size of the hemoperitoneum help to discriminate the bleeding source and guide therapeutic decisions in blunt trauma patients with pelvic ring fracture? Charbit J, Millet I, Martinez O, Roustan JP, Merigeaud S, Taourel P, Capdevila X. J Trauma Acute Care Surg. 2012 Jul;73(1):117-125. (IF= 3.13).
45. Right phrenic stimulation due to defibrillator implantation: A rare cause / Stimulation diaphragmatique droite suite à l’implantation d’un défibrillateur : une étiologie rare.  François Roubille, François Massin, Jean-Marc Davy. Archives of Cardiovascular Diseases  2012 Apr;105(4):256-7 (IF = 1.21).
46. 14q12 and severe Rett-like phenotypes: new clinical insights and physical mapping of FOXG1-regulatory elements. Allou L, Lambert L, Amsallem D, Bieth E, Edery P, Destrée A, Rivier F, Amor D, Thompson E, Nicholl J, Harbord M, Nemos C, Saunier A, Moustaïne A, Vigouroux A, Jonveaux P, Philippe C. Eur J Hum Genet. 2012 Dec;20(12):1216-1223 (IF =4.38).
47. Maximal lipid oxidation during exercise: a target for individualizing endurance training in obesity and diabetes? Brun JF, Malatesta D, Sartorio A. J Endocrinol Invest. 2012 Jul;35(7):686-691.IF =1,47).
48. Clinical review: Update on neurally adjusted ventilatory assist - report of a round-table conference. Terzi N, Piquilloud L, Rozé H, Mercat A, Lofaso F, Delisle S, Jolliet P, Sottiaux T, Tassaux D, Roesler J, Demoule A, Jaber S, Mancebo J, Brochard L, Richard JC. Crit Care. 2012 Jun 20;16(3):225. (IF =4.96).
49. Paradoxical Effect of Increased Diastolic Ca2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia. Neco P, Torrente A, Mesirca P, Zorio E, Liu N, Priori SG, Napolitano C, Richard S, Benitah JP, Mangoni ME, Gómez AM. Circulation. 2012 Jul 24;126(4):392-401, (IF =14.93).
50. A multicentre observational study of intra-operative ventilatory management during general anaesthesia: tidal volumes and relation to body weight. Jaber S, Coisel Y, Chanques G, Futier E, Constantin JM, Michelet P, Beaussier M, Lefrant JY, Allaouchiche B, Capdevila X, Marret E. Anaesthesia. 2012 Sep;67(9):999-1008 (IF=3,01).
51. Carbon monoxide exposure in the urban environment: An insidious foe for the heart? Reboul C, Thireau J, Meyer G, Lucas A, Obert P, Cazorla O, Richard S. Respir Physiol Neurobiol. 2012 184, (2), Nov 15, 204–212,  (IF = 2.38).
52. Homocysteine as a determinant of left ventricular ejection fraction in patients with diabetes. Badiou S, Dupuy AM, Jaussent I, Sultan A, Mariano-Goulart D, Cristol JP, Avignon A. Clin Chem Lab Med. 2012 Mar 29;50(6), 1099-106. (IF=2.06).
53.  The RNA-Binding Protein RBPMS2 Regulates Development of Gastrointestinal Smooth Muscle. Notarnicola C, Rouleau C, Le Guen L, Virsolvy A, Richard S, Faure S, de Santa Barbara P.  Gastroenterology. 2012 Sep;143(3):687-697 (IF =12.40).
54. AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm.  Pauly M, Daussin F, Burelle Y, Li T, Godin R, Fauconnier J, Koechlin-Ramonatxo C, Hugon G, Lacampagne A, Quivy M, Liang F, Hussain S, Matecki S, Petrof BJ.  Am J Pathol. 2012 Aug;181(2):583-92. (IF =5.97).
55. E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism. Emilie Blanchet, Jean-Sébastien  Annicotte, Ludivine A. Pradelli, Gérald Hugon, Stéfan Matecki, Dominique Mornet, François Rivier, and Lluis Fajas Hum. Mol. Genet. 2012 Sep 1;21(17):3910-7.  (IF = 8.14).
56. Obesity and mortality in critically ill patients: another case of the Simpson paradox? De Jong A, Jung B, Chanques G, Jaber S, Molinari N. Chest. 2012 Jun; 141(6):1637-8. (IF = 6.51).
57. Limited Short-term Steroid Responsiveness Is Associated With Thickening of Bronchial Basement Membrane in Severe Asthma. Bourdin A, Kleis S, Chakra M, Vachier I, Paganin F, Godard P, Chanez P. Chest. 2012 Jun;141(6):1504-11. (IF = 6.51). 
58. Endoluminal treatment of dissecting aortic arch aneurysm after surgical treatment of acute type a dissection. Canaud L, Demaria R, Joyeux F, Hireche K, Berthet JP, D'Annoville T, Marty-Ané C, Alric P. Ann Vasc Surg. 2012 Jul;26(5):715-9.(IF = 1.44).
59. Protein kinase D increases maximal Ca2+-activated tension of cardiomyocyte contraction by phosphorylation of cMyBP-C-Ser315. Dirkx E, Cazorla OF, Schwenk RW, Lorenzen-Schmidt I, Sadayappan S, Van Lint J, Carrier L, van Eys GJ, Glatz JF, Luiken JJ. Am J Physiol Heart Circ Physiol. 2012 Aug;303(3):H323-31. (IF = 3.88).
60. Decreased fat oxidation during exercise in severe obstructive sleep apnoea syndrome. Desplan M, Brun JF, Pillard F, Fedou C, Prefaut C, Mercier J, Dauvilliers Y, Avignon A. Diabetes Metab. Diabetes Metab. 2012 Jun;38(3):236-42 (IF = 3.03).
61. Safety and pharmacokinetics of an anti-PcrV PEGylated monoclonal antibody fragment in mechanically ventilated patients colonized with Pseudomonas aeruginosa: A randomized, double-blind, placebo-controlled trial. François B, Luyt CE, Dugard A, Wolff M, Diehl JL, Jaber S, Forel JM, Garot D, Kipnis E, Mebazaa A, Misset B, Andremont A, Ploy MC, Jacobs A, Yarranton G, Pearce T, Fagon JY, Chastre J. Crit Care Med. 2012 Aug;40(8):2320-2326, (IF=6.45).
62.  Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression.  Eaton A, Nagy E, Pacault M, Fauconnier J, Bäck M. J Mol Med (Berl). 2012 Oct;90(10):1223-31. (IF = 5.19).
63. Functional evidence for an active role of B-type natriuretic peptide in cardiac remodeling and pro-arrhythmogenicity. Thireau J, Karam S, Fauconnier J, Roberge S, Cassan C, Cazorla O, Aimond F, Lacampagne A, Babuty D, Richard S. Cardiovasc Res. 2012 Jul 1;95(1):59-68. (IF=6.05).
64. Hepatic Artery Kinking during Liver Transplantation : Survey and Prospective Intraoperative Flow Measurement. Panaro F, Bouyabrine H, Carabalona JP, Marchand JP, Jaber S, Navarro F. J Gastrointest Surg. 2012 Aug;16(8):1524-30 (IF= 2.73).
65. Bradykinin restores left ventricular function, sarcomeric protein phosphorylation and e/nNOs levels in dogs with Duchenne muscular dystrophy cardiomyopathy. Su JB, Cazorla O, Blot S, Blanchard-Gutton N, Ait Mou Y, Barthélémy I, Sambin L, Sampedrano CC, Gouni V, Unterfinger Y, Aguilar P, Thibaud JL, Bizé A, Pouchelon JL, Dabiré H, Ghaleh B, Berdeaux A, Chetboul V, Lacampagne A, Hittinger L. Cardiovasc Res. 2012 Jul 1;95(1):86-96. (IF=6.05).
66. Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey. Selton-Suty C, Célard M, Le Moing V, Doco-Lecompte T, Chirouze C, Iung B, Strady C, Revest M, Vandenesch F, Bouvet A, Delahaye F, Alla F, Duval X, Hoen B; AEPEI Study Group. Clin Infect Dis. 2012 May;54(9):1230-9.(IF = 8.18).
67. Hemodynamic Profile of Target-Controlled Spinal Anesthesia Compared With 2 Target-Controlled General Anesthesia Techniques in Elderly Patients With Cardiac Comorbidities. Biboulet P, Jourdan A, Van Haevre V, Morau D, Bernard N, Bringuier S, Capdevila X. Reg Anesth Pain Med. 2012 Jul;37(4):433-40. (IF=2.80).
68. Ultrasound guidance characteristics and efficiency of suprazygomatic maxillary nerve blocks in infants: a descriptive prospective study. Sola C, Raux O, Savath L, Macq C, Capdevila X, Dadure C. Paediatr Anaesth. 2012 Sep;22(9):841-6. (IF= 2.17).
69. Dietary antioxidants: Do they have a role to play in the ongoing fight against abnormal glucose metabolism? Avignon A, Hokayem M, Bisbal C, Lambert K. Nutrition. 2012 Jul; 28(7-8):715-21. (IF= 2.73).
70. Health-related quality of life and stages of behavioural change for exercise in overweight/obese individuals. Romain AJ, Bernard P, Attalin V, Gernigon C, Ninot G, Avignon A. Diabetes Metab. 2012 Oct;38(4):352-8. (IF = 3.03).
71. Clinical inertia: viewpoints of general practitioners and diabetologists. Avignon A, Attali C, Sultan A, Ferrat E, Le Breton J. Diabetes Metab. 2012 Mar;38 Suppl 3:S53-8. (IF = 3.03).
72. Type 2 diabetes treatment intensification in general practice in France in 2008-2009: the DIAttitude Study. Balkau B, Bouée S, Avignon A, Vergès B, Chartier I, Amelineau E, Halimi S. Diabetes Metab. 2012 Mar; 38 Suppl 3:S29-35. (IF = 3.03).
73. Clinical review: Respiratory monitoring in the ICU - a consensus of 16. Brochard L, Martin GS, Blanch L, Pelosi P, Belda FJ, Jubran A, Gattinoni L, Mancebo J, Ranieri VM, Richard JC, Gommers D, Vieillard-Baron A, Pesenti A, Jaber S, Stenqvist O, Vincent JL. Crit Care. 2012 Apr 26;16(2):219. (IF =4.96).
74. [Anaesthetic management of brain-dead for organ donation: impact on delayed graft function after kidney transplantation.] Boutin C, Vachiéry-Lahaye F, Alonso S, Louart G, Bouju A, Lazarovici S, Perrigault PF, Capdevila X, Jaber S, Colson P, Jonquet O, Ripart J, Lefrant JY, Muller L; pour le groupe AzuRéa. Ann Fr Anesth Reanim. 2012 May;31(5):427-36. (IF = 0.88).
75. Immunohistochemical analysis of bone morphological protein signaling pathway in human myometrium. Rouleau C, Rico C, Hapkova I, de Santa Barbara P. Exp Mol Pathol. 2012 Apr 17;93(1):56-60. (IF= 2.98).
76. Ventilator-associated pneumonia and ICU mortality in severe ARDS patients ventilated according to a lung-protective strategy. Forel JM, Voillet F, Pulina D, Gacouin A, Perrin G, Barrau K, Jaber S, Arnal JM, Fathallah M, Auquier P, Roch A, Azoulay E, Papazian L. Crit Care. 2012 Apr 23;16(2):R65. (IF =4.96).
77. Pulmonary hypertension associated with benfluorex exposure. Savale L, Chaumais MC, Cottin V, Bergot E, Frachon I, Prevot G, Pison C, Dromer C, Poubeau P, Lamblin N, Habib G, Reynaud-Gaubert M, Bourdin A, Sanchez O, Tubert-Bitter P, Jaïs X, Montani D, Sitbon O, Simonneau G, Humbert M. Eur Respir J. 2012 Nov;40(5):1164-72. (IF=6,22).
78. Excessive alcohol consumption after liver transplantation impacts on long-term survival, whatever the primary indication. Faure S, Herrero A, Jung B, Duny Y, Daures JP, Mura T, Assenat E, Bismuth M, Bouyabrine H, Donnadieu-Rigole H, Navarro F, Jaber S, Larrey D, Pageaux GP. J Hepatol. 2012 Aug;57(2):306-12. (IF= 9.33).
79. Ultrasound-guided nerve blocks: the real position of the needle should be defined. Choquet O, Capdevila X. Anesth Analg. 2012 May;114(5):929-30.(IF = 3.27
80. Comprehensive oligonucleotide array-comparative genomic hybridization analysis: new insights into the molecular pathology of the DMD gene. Ishmukhametova A, Van Kien PK, Méchin D, Thorel D, Vincent MC, Rivier F, Coubes C, Humbertclaude V, Claustres M, Tuffery-Giraud S. Eur J Hum Genet. 2012 Oct;20(10):1096-100 (IF =4.38).
81. Reply to the editor. Canaud L, Alric P. J Thorac Cardiovasc Surg. 2012 May; 143(5):1230-1. (IF=3,61).
82. Multi-cytokine detection improves latent tuberculosis diagnosis in healthcare workers. Rubbo PA, Nagot N, Le Moing V, Brabet M, Bourdin A, Nogue E, Bollore K, Vendrell JP, Van De Perre P, Tuaillon E. J Clin Microbiol. 2012 May;50(5):1711-7 (IF= 4.25).
83. Near Elimination of Ventricular Pacing in SafeR Mode Compared to DDD Modes: A Randomized Study of 422 Patients. Davy JM, Hoffmann E, Frey A, Jocham K, Rossi S, Dupuis JM, Frabetti L, Ducloux P, Prades E, Jauvert G. Pacing Clin Electrophysiol. 2012 Apr;35(4):392-402 (IF=1,35).
84.  Resveratrol and diabetic cardiac function: focus on recent in vitro and in vivo studies. Turan B, Tuncay E, Vassort G.  J Bioenerg Biomembr. 2012 Apr; 44(2):281-96. (IF = 3.67).
85. Distinguishing colonization from infection with Staphylococcus aureus in diabetic foot ulcers with miniaturized oligonucleotide arrays: a French multicenter study. Sotto A, Richard JL, Messad N, Molinari N, Jourdan N, Schuldiner S, Sultan A, Carrière C, Canivet B, Landraud L, Lina G, Lavigne JP; French Study Group on the Diabetic Foot. Diabetes Care. 2012 Mar;35(3):617-23.(IF = 7.28).
86. [A new complication related to prolonged prone position: a masseter muscle haematoma]. Abbal B, Choquet O, Gourari A, Capdevila X. Ann Fr Anesth Reanim. 2012 Feb; 31(2):166-8. (IF =0.88).
87. [Peripheral nerve blocks of the face in children]. Dadure C, Sola C, Choquet O, Capdevila X. Ann Fr Anesth Reanim. 2012 Jan; 31(1):e17-20. (IF =0.88).
88. A Randomized Study of Defibrillator Lead Implantations in the Right Ventricular Mid-Septum versus the Apex: The SEPTAL Study(τ). Mabo P, Defaye P, Cebron JP, Mouton E, Davy JM, Tassin A, Babuty D, Mondoly P, Paziaud O, Anselme F, Daubert JC. J Cardiovasc Electrophysiol. 2012 Aug;23(8):853-860. (IF = 3.29).
89. Pulmonary Arterial Hypertension in Patients Treated by Dasatinib. Montani D, Bergot E, Günther S, Savale L, Bergeron A, Bourdin A, Bouvaist H, Canuet M, Pison C, Macro M, Poubeau P, Girerd B, Natali D, Guignabert C, Perros F, O'Callaghan DS, Jaïs X, Tubert-Bitter P, Zalcman G, Sitbon O, Simonneau G, Humbert M. Circulation. 2012 May 1;125(17):2128-37. (IF =14.93).
90. Organ volume measurements: comparison between MRI and autopsy findings in infants following sudden unexpected death. Prodhomme O, Seguret F, Martrille L, Pidoux O, Cambonie G, Couture A, Rouleau C. Arch Dis Child Fetal Neonatal Ed. 2012 Nov;97(6):F434-8, (IF = 3.13).
91. Radioguided occult lesion localization plus sentinel node biopsy (SNOLL) versus wire-guided localization plus sentinel node detection: a case control study of 129 unifocal pure invasive non-palpable breast cancers. Giacalone PL, Bourdon A, Trinh PD, Taourel P, Rathat G, Sainmont M, Perocchia H, Rossi M, Rouleau C. Eur J Surg Oncol. 2012 Mar;38(3):222-9. (IF = 2.77).
92. Cobblestone lissencephaly: neuropathological subtypes and correlations with genes of dystroglycanopathies. Devisme L, Bouchet C, Gonzalès M, Alanio E, Bazin A, Bessières B, Bigi N, Blanchet P, Bonneau D, Bonnières M, Bucourt M, Carles D, Clarisse B, Delahaye S, Fallet-Bianco C, Figarella-Branger D, Gaillard D, Gasser B, Delezoide AL, Guimiot F, Joubert M, Laurent N, Laquerrière A, Liprandi A, Loget P, Marcorelles P, Martinovic J, Menez F, Patrier S, Pelluard F, Perez MJ, Rouleau C, Triau S, Attié-Bitach T, Vuillaumier-Barrot S, Seta N, Encha-Razavi F. Brain. 2012 Feb;135(Pt 2):469-82. (IF = 10.14).
93. RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation. Fabre O, Salehzada T, Lambert K, Boo Seok Y, Zhou A, Mercier J, Bisbal C. Cell Death Differ. 2012 Sep;19(9):1470-81 (IF 9.05).
94.  Cardiac arrhythmia mechanisms in rats with heart failure induced by pulmonary hypertension. Benoist D, Stones R, Drinkhill MJ, Benson AP, Yang Z, Cassan C, Gilbert SH, Saint DA, Cazorla OF, Steele DS, Bernus O, White E. Am J Physiol Heart Circ Physiol. 2012 Jun;302(11):H2381-95. (IF= 3.88).
95. Noninvasive monitoring of blood pressure in the critically ill: Reliability according to the cuff site (arm, thigh, or ankle). Lakhal K, Macq C, Ehrmann S, Boulain T, Capdevila X. Crit Care Med. 2012 Apr;40(4):1207-13. (IF=6.45).
96. Absence of Triadin, a Protein of the Calcium Release Complex, is Responsible forCardiac Arrhythmia with Sudden Death in Human. Nathalie Roux-Buisson, Marine Cacheux, Anne Fourest-Lieuvin, Jeremy Fauconnier, Julie Brocard, Isabelle Denjoy, Philippe Durand, Pascale Guicheney, Florence Kyndt, Antoine Leenhardt, Hervé Le Marec, Vincent Lucet, Philippe Mabo, Vincent Probst, Nicole Monnier, Pierre F. Ray, Elodie Santoni, PaulineTrémeaux, Alain Lacampagne, Julien Fauré, Joël Lunardi, Isabelle Marty. Human Molec Genet, 2012 Jun 15;21(12):2759-67. (IF = 8.14).
97. An ex vivo model of severe asthma using reconstituted human bronchial epithelium. Gras D, Bourdin A, Vachier I, de Senneville L, Bonnans C, Chanez P. J Allergy Clin Immunol.  2012 May;129(5):1259-1266.e1.  (IF = 9.27)
98. Interaction between maternal obesity and post-natal over-nutrition on skeletal muscle metabolism. Simar D, Chen H, Lambert K, Mercier J, Morris MJ. Nutr Metab Cardiovasc Dis. 2012 Mar;22(3):269-76. (IF =3,52).
99. In reply. Dadure C, Capdevila X. Anesthesiology. 2012 Mar;116(3):734. (IF =5.48).
100. The combination of polytetrafluoroethylene mesh and titanium rib implants: an innovative process for reconstructing large full thickness chest wall defects. Berthet JP, Wihlm JM, Canaud L, Joyeux F, Cosma C, Hireche K, Alric P, Marty-Ané CH. Eur J Cardiothorac Surg. 2012 Sep;42(3):444-53. (IF=2.37).
101. Physical-activity prescription for obesity management in primary care: Attitudes and practices of GPs in a southern French city. Attalin V, Romain AJ, Avignon A. Diabetes Metab. 2012 Jun;38(3):243-9. (IF=3.03).
102. Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock. Muller L, Jaber S, Molinari N, Favier L, Larche J, Motte G, Lazarovici S, Jacques L, Alonso S, Leone M, Constantin JM, Allaouchiche B, Suehs C, Lefrant JY, Group A. Crit Care. 2012 Feb 29; 16(1):R34. (IF =4.96).
103. PALLAS: Insights into permanent atrial fibrillation. Davy JM, Roubille F, Pasquié JL. Arch Cardiovasc Dis. 2012 Jan; 105(1):1-4 (IF =1.21).
104. Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes. Sassi Y, Abi-Gerges A, Fauconnier J, Mougenot N, Reiken S, Haghighi K, Kranias EG, Marks AR, Lacampagne A, Engelhardt S, Hatem SN, Lompre AM, Hulot JS. FASEB J. 2012Mar; 26(3): 1009-17. (IF =6,40).
105. Respiratory preparation before surgery in patients with chronic respiratory failure.] Delay JM, Jaber S. Presse Med. 2012 Mar;41(3 Pt 1):225-33, (IF =0.48).
106. Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins. Sirvent P, Fabre O, Bordenave S, Hillaire-Buys D, de Mauverger ER, Lacampagne A, Mercier J. Toxicol Appl Pharmacol. 2012 Mar 1;259(2):263-8, (IF= 4.25).
107. M19 Modulates Skeletal Muscle Differentiation and Insulin Secretion in Pancreatic b-Cells through Modulation of Respiratory Chain Activity. Linda Cambier, Patrice Rassam, Béatrice Chabi, Karima Mezghenna, René Gross, Eric Eveno, Charles Auffray, Chantal Wrutniak-Cabello, Anne-Dominique Lajoix, and Pascal Pomiès.  PLoS ONE,   2012:7(2); e31815. (IF = 4.61).
108. Upregulation of brain utrophin does not overcome behavioral alterations in dystrophin-deficient mice. Perronnet C, Chagneau C, Samson-Desvignes N, Leblanc-Veyrac P, Mornet D, Laroche S, De La Porte S, Vaillend C. Human Molecular Genetics 2012 May 15;21(10):2263-76 (IF = 8.14).
109. Motor and respiratory heterogeneity in Duchenne patients: Implication for clinical trials. Humbertclaude V, Hamroun D, Bezzou K, Bérard C, Boespflug-Tanguy O, Bommelaer C, Campana-Salort E, Cances C, Chabrol B, Commare MC, Cuisset JM, de Lattre C, Desnuelle C, Echenne B, Halbert C, Jonquet O, Labarre-Vila A, N'guyen-Morel MA, Pages M, Pepin JL, Petitjean T, Pouget J, Ollagnon-Roman E, Richelme C, Rivier F, Sacconi S, Tiffreau V, Vuillerot C, Picot MC, Claustres M, Béroud C, Tuffery-Giraud S. Eur J Paediatr Neurol. 2012 Mar;16(2):149-60. (IF : 1.99).
110. Relationships between insulin sensitivity measured with the oral minimal model and blood rheology. Brun JF, Varlet-Marie E, de Mauverger ER. Clin Hemorheol Microcirc. 2012 Jan 1;51(1):29-34. (IF = 3.39).
111. Hyperventilation during Exercise in Very Low Birth Weight School-Age Children may Implicate Inspiratory Muscle Weakness. Rideau Batista Novais A, Matecki S, Jaussent A, Picot MC, Amedro P, Guillaumont S, Picaud JC, Cambonie G.  J Pediatr. 2012 Mar;160(3):415-420 (IF =4,20).
112. ACE Inhibition Prevents Diastolic Ca2+ Overload and Loss of Myofilament Ca2+ Sensitivity after Myocardial Infarction. Zalvidea S, Andre L, Loyer X, Cassan C, Sainte-Marie Y, Thireau J, Sjaastad I, Heymes C, Pasquie JL, Cazorla O, Aimond F, Richard S.  Curr Mol Med. 2012 Feb 1;12(2):206-17;  (IF = 5.21).
113. Subclinical atrial fibrillation and the risk of stroke. Healey JS, Connolly SJ, Gold MR, Israel CW, Van Gelder IC, Capucci A, Lau CP, Fain E, Yang S, Bailleul C, Morillo CA, Carlson M, Themeles E, Kaufman ES, Hohnloser SH; ASSERT Investigators, (….. including, J.M. Davy). N Engl J Med. 2012 Jan 12;366(2):120-9. (IF = 53.48).
114. Six-minute walking test predicts maximal fat oxidation in obese children. Makni E, Moalla W, Trabelsi Y, Lac G, Brun JF, Tabka Z, Elloumi M. Int J Obes (Lond). 2012 Jul;36(7):908-13. (IF =5.12).
115. Influence of opioid choice on mechanical ventilation duration and ICU length of stay. Futier E, Chanques G, Cayot Constantin S, Vernis L, Barres A, Guerin R, Chartier C, Perbet S, Petit A, Jabaudon M, Bazin JE, Constantin JM. Minerva Anestesiol. 2012 Jan;78(1):46-53. (IF=2,58).
116. Peripheral catheter techniques.  Dadure C, Capdevila X. Paediatr Anaesth. 2012 Jan; 22(1):93-101. (IF=2.17).
117. Minimal model-derived insulin sensitivity, insulin secretion and glucose tolerance: relationships with blood rheology. Brun JF, Varlet-Marie E, de Mauverger ER, Mercier J. Clin Hemorheol Microcirc. 2012 Jan 1;51(1):21-7. (IF = 3.39).
118. Effect of acute and short-term oral salbutamol treatments on maximal power output in non-asthmatic athletes. Sanchez AM, Collomp K, Carra J, Borrani F, Coste O, Préfaut C, Candau R. Eur J Appl Physiol. 2012 Sep;112(9):3251-8 (IF = 2.52).
119. Effects of acute and chronic exercise on sarcolemmal MCT1 and MCT4 contents in human skeletal muscles: Current Status. Thomas C, Bishop DJ, Lambert K, Mercier J, Brooks GA. Am J Physiol Regul Integr Comp Physiol. 2012 Jan;302(1):R1-R14. (IF = 3.39).
120. Intraoperative use of transoesophageal Doppler to predict response to volume expansion in infants and neonates. Raux O, Spencer A, Fesseau R, Mercier G, Rochette A, Bringuier S, Lakhal K, Capdevila X, Dadure C. Br J Anaesth. 2012 Jan;108(1):100-7.  IF: 4.22).
121. Consensus statement on the care of the hyperglycaemic/diabetic patient during and in the immediate follow-up of acute coronary syndrome. Vergès B, Avignon A, Bonnet F, Catargi B, Cattan S, Cosson E, Ducrocq G, Elbaz M, Fredenrich A, Gourdy P, Henry P, Lairez O, Leguerrier AM, Monpère C, Moulin P, Vergès-Patois B, Roussel R, Steg G, Valensi P; Diabetes and Cardiovascular Disease study group of the Société francophone du diabète (SFD), in collaboration with the Société française de cardiologie (SFC). Diabetes Metab. 2012 Apr;38(2):113-27 (IF = 3.03).
122. Role of organisational structure in implementation of sedation protocols: a comparison of Canadian and French ICUs. Dodek P, Chanques G, Brown G, Norena M, Grubisic M, Wong H, Jaber S. BMJ Qual Saf. 2012 Sep;21(9):715-21. (IF: 2,85).

Year  2011

• Efficacy and safety of celivarone, with amiodarone as calibrator, in patients with an implantable cardioverter-defibrillator for prevention of implantable cardioverter-defibrillator interventions or death: the ALPHEE study. Kowey PR, Crijns HJ, Aliot EM, Capucci A, Kulakowski P, Radzik D, Roy D, Connolly SJ, Hohnloser SH; ALPHEE Study Investigators, (…… including Pasquie JL,).Circulation.2011 Dec 13; 124(24):2649-60. (IF =14.93
• Blood rheology and body composition as determinants of exercise performance in male soccer players. Varlet-Marie E, Brun JF, Fédou C, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2011 Jan 1;49(1):225-30. (IF = 2,84)
• Body composition and exercise performance as determinants of blood rheology in middle-aged patients exhibiting the metabolic syndrome. Brun JF, Varlet-Marie E, Fédou C, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2011 Jan 1;49(1):215-23. (IF = 2,84)

• Blood rheology and body composition as determinants of exercise performance in female rugby players. Brun JF, Varlet-Marie E, Cassan D, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2011 Jan 1;49(1):207-14. (IF = 2,84) 
• Effects of exercise training on blood rheology: A meta-analysis. Romain AJ, Brun JF, Varlet-Marie E, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2011 Jan 1;49(1):199-205. (IF = 2,84)
• Interrelationships among body composition, blood rheology and exercise performance. Brun JF, Varlet-Marie E, Romain AJ, Raynaud de Mauverger E. Clin Hemorheol Microcirc. 2011 Jan 1;49(1):183-97. (IF = 2,84)
• Swallowing disorders, pneumonia and respiratory tract infectious disease in the elderly. Puisieux F, D'Andrea C, Baconnier P, Bui-Dinh D, Castaings-Pelet S, Crestani B, Desrues B, Ferron C, Franco A, Gaillat J, Guenard H, Housset B, Jeandel C, Jebrak G, Leymarie-Saddles A, Orvoen-Frija E, Piette F, Pinganaud G, Salle JY, Strubel D, Vernejoux JM, de Wazières B, Weil-Engerer S; Intergroupe PneumoGériatrie SPLF–SFGG placé sous l’égide de la Société de pneumologie de langue française (SPLF) et de la Société française de gériatrie et gérontologie (SFGG) ), (……. Including M Hayot, C Prefaut). Rev Mal Respir. 2011 Oct;28(8):e76-93. (IF= 0,43)
• Increased FAT/CD36 Cycling and Lipid Accumulation in Myotubes Derived from Obese Type 2 Diabetic Patients. Aguer C, Foretz M, Lantier L, Hebrard S, Viollet B, Mercier J, Kitzmann M. PLoS One. 2011;6(12):e28981.(IF : 4,38)
• [Airway remodeling in asthma: clinical and functional correlates]. Gras D, Bourdin A, Chanez P, Vachier I. Med Sci (Paris). 2011 Nov;27(11):959-65. (IF=0,65)
• A retroperitoneal fibrous lesion with a specific CTNNB1 mutation but absence of beta-catenin immunodetection: benign process or unusual desmoid-type fibromatosis? Rouleau C, Vernhet H, Marty M, Hostein I, Alric P, Coindre JM. Pathology. 2011 Dec;43(7):751-3.(IF = 2.31)
• Dronedarone in High-Risk Permanent Atrial Fibrillation. Connolly SJ, Camm AJ, Halperin JL, Joyner C, Alings M, Amerena J, Atar D, Avezum A, Blomström P, Borggrefe M, Budaj A, Chen SA, Ching CK, Commerford P, Dans A, Davy JM, Delacrétaz E, Di Pasquale G, Diaz R, Dorian P, Flaker G, Golitsyn S, Gonzalez-Hermosillo A, Granger CB, Heidbüchel H, Kautzner J, Kim JS, Lanas F, Lewis BS, Merino JL, Morillo C, Murin J, Narasimhan C, Paolasso E, Parkhomenko A, Peters NS, Sim KH, Stiles MK, Tanomsup S, Toivonen L, Tomcsányi J, Torp-Pedersen C, Tse HF, Vardas P, Vinereanu D, Xavier D, Zhu J, Zhu JR, Baret-Cormel L, Weinling E, Staiger C, Yusuf S, Chrolavicius S, Afzal R, Hohnloser SH; the PALLAS Investigators. N Engl J Med. 2011 Dec 15;365(24):2268-76. (IF = 53.48).
• The FSHD Atrophic Myotube Phenotype Is Caused by DUX4 Expression. Vanderplanck C, Ansseau E, Charron S, Stricwant N, Tassin A, Laoudj-Chenivesse D, Wilton SD, Coppée F, Belayew A. PLoS One. 2011;6(10):e26820. (IF : 4,38)
• Atypical RhoV and RhoU GTPases control development of the neural Crest.  Sandrine  Faure  and Philippe Fort. Small GTPases 2:6, 1–4; November/December 2011; G 2011 Landes Bioscience
• [Causes of early mortality after liver transplantation: A twenty-years single centre experience.] Jung B, Cisse M, Chanques G, Arsac E, Bismuth M, Panaro F, Perrigault PF, Souche B, Gallix B, Verzilli D, Delay JM, Navarro F, Pageaux GP, Jaber S. Ann Fr Anesth Reanim. 2011 Dec;30(12):899-904.  (IF = 0.88)
• Both overall adiposity and abdominal adiposity increase blood viscosity by separate mechanisms.   Brun JF, Varlet-Marie E, Raynaud de Mauverger E, Mercier J. Clin Hemorheol Microcirc. 2011 Jan 1;48(4):257-63. (IF = 2,84)
• Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and impact of buffer therapy: a prospective, multiple-center study. Jung B, Rimmele T, Le Goff C, Chanques G, Corne P, Jonquet O, Muller L, Lefrant JY, Guervilly C, Papazian L, Allaouchiche B, Jaber S, Azurea Group T. Crit Care. 2011 Oct 13;15(5):R238. (IF : 4,93)
• [Non-communicable chronic diseases, a global public health priority recognized by the United Nations].Bousquet J; Groupe d'étude Clinique Maladies Chroniques Languedoc-Roussillon,( …..including  Antoine Avignon, Jacques Mercier ,  Christian Préfaut, ).    Presse Med. 2011 Sep;40(9 Pt 1):787-9. (IF=0.48).
• The Kruppel-like factor 15 as a molecular link between myogenic factors and a chromosome 4q transcriptional enhancer implicated in facioscapulohumeral dystrophy. Dmitriev P, Petrov A, Ansseau E, Stankevicins L, Charron S, Kim E, Bos TJ, Robert T, Turki A, Coppee F, Belayew A, Lazar V, Carnac G, Laoudj-Chenivesse D, Lipinski M, Vassetzky YS. J Biol Chem. 2011 Dec 30;286(52):44620-31., (IF = 5.49).
• A missense mutation within the fork-head domain of the forkhead box G1 Gene (FOXG1) affects its nuclear localization. Le Guen T, Fichou Y, Nectoux J, Bahi-Buisson N, Rivier F, Boddaert N, Diebold B, Héron D, Chelly J, Bienvenu T. Hum Mutat. 2011 Feb;32(2):E2026-35. (IF : 6.21)
• Multicentric Retrospective Study of Endovascular Treatment for Restenosis after Open Carotid Surgery. Midy D, Berard X, Becquemin JP, Patra P, Alric P, Derrider P, Magnan PE; Association Universitaire de Recherche en Chirurgie Vasculaire., Eur J Vasc Endovasc Surg. 2011 Dec;42(6):742-50. (IF: 2.90)
• Spirometric profile of narghile smokers. Ben Saad H, Khemis M, Bougmiza I, Préfaut C, Aouina H, Mrizek N, Garrouche A, Zbidi A, Tabka Z. Rev Mal Respir. 2011 Sep;28(7):e39-e51. (IF= 0,43)
• The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine. Potier M, Chantome A, Joulin V, Girault A, Roger S, Besson P, Jourdan ML, Le Guennec JY, Bougnoux P, Vandier C. Br J Pharmacol. 2011 Jan;162(2):464-79. (IF: 4.92)
• Endovascular Repair of Aorto-iliac Artery Injuries after Lumbar-spine Surgery.Canaud L, Hireche K, Joyeux F, D'Annoville T, Berthet JP, Marty-Ané C, Alric P. Eur J Vasc Endovasc Surg. 2011 Aug;42(2):167-71. (IF: 2.90)
• Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor. Chauvier D, Renolleau S, Holifanjaniaina S, Ankri S, Bezault M, Schwendimann L, Rousset C, Casimir R, Hoebeke J, Smirnova M, Debret G, Trichet AP, Carlsson Y, Wang X, Bernard E, Hébert M, Rauzier JM, Matecki S, Lacampagne A, Rustin P, Mariani J, Hagberg H, Gressens P, Charriaut-Marlangue C, Jacotot E. Cell Death Dis. 2011 Sep 1;2:e203.
• Polyphenols prevent lipid abnormalities and arterial dysfunction in hamsters on a high-fat diet: a comparative study of red grape and white persimmon wines. Suh JH, Virsolvy A, Goux A, Cassan C, Richard S, Cristol JP, Teissèdre PL, Rouanet JM. Food Funct. 2011 Sep 16;2(9):555-61.
• Evidence of an early physical activity reduction in chronic obstructive pulmonary disease patients. Gouzi F, Préfaut C, Abdellaoui A, Vuillemin A, Molinari N, Ninot G, Caris G, Hayot M. Arch Phys Med Rehabil. 2011 Oct;92(10):1611-1617. (IF: 2.73 )
• Impact of stent-graft development on outcome of endovascular repair of acute traumatic transection of the thoracic aorta. Canaud L, Joyeux F, Berthet JP, Hireche K, Marty-Ané C, Alric P. J Endovasc Ther. 2011 Aug;18(4):485-90. (IF : 2.94)
• Ryanodine receptor: a new therapeutic target to control diabetic cardiomyopathy. Turan B, Vassort G. Antioxid Redox Signal. 2011 Oct 1;15(7):1847-61. (IF : 7,58)
• Physical activity and sarcopenia. Pillard F, Laoudj-Chenivesse D, Carnac G, Mercier J, Rami J, Rivière D, Rolland Y. Clin Geriatr Med. 2011 Aug;27(3):449-70. (IF : 1.63)
• Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress. André L, Gouzi F, Thireau J, Meyer G, Boissiere J, Delage M, Abdellaoui A, Feillet-Coudray C, Fouret G, Cristol JP, Lacampagne A, Obert P, Reboul C, Fauconnier J, Hayot M, Richard S, Cazorla O. Basic Res Cardiol. 2011 Nov;106(6):1235-46. (IF : 6.12).
• Critical Role for Stromal Interaction Molecule 1 in Cardiac Hypertrophy. Hulot JS, Fauconnier J, Ramanujam D, Chaanine A, Aubart F, Sassi Y, Merkle S, Cazorla O, Ouillé A, Dupuis M, Hadri L, Jeong D, Mühlstedt S, Schmitt J, Braun A, Bénard L, Saliba Y, Laggerbauer B, Nieswandt B, Lacampagne A, Hajjar RJ, Lompré AM, Engelhardt S. Circulation. 2011 Aug 16;124(7):796-805 (IF: 14.93).
• Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging. Andersson DC, Betzenhauser MJ, Reiken S, Meli AC, Umanskaya A, Xie W, Shiomi T, Zalk R, Lacampagne A, Marks AR. Cell Metab. 2011 Aug 3;14(2):196-207(IF : 20,13)
• Vitamin E in Oxidant Stress-Related Cardiovascular Pathologies: Focus on Experimental Studies. Turan B, Vassort G. Curr Pharm Des. 2011;17(21):2155-69. (IF : 4.77)
• Synthesis of Mannose-6-Phosphate Analogues and their Utility as Angiogenesis Regulators. Barragan-Montero V, Awwad A, Combemale S, de Santa Barbara P, Jover B, Molès JP, Montero JL. Chem Med Chem. 2011 Oct 4;6(10):1771-4. (IF : 3.30)
• Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion. Fauconnier J, Meli AC, Thireau J, Roberge S, Shan J, Sassi Y, Reiken SR, Rauzier JM, Marchand A, Chauvier D, Cassan C, Crozier C, Bideaux P, Lompré AM, Jacotot E, Marks AR, Lacampagne A. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13258-63 (IF : 10.59)
• Systems medicine and integrated care to combat chronic noncommunicable diseases. Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Genome Med. 2011 Jul 6;3(7):43.
• R2: The Absence of Adrenal Gland Enlargement during Septic Shock Predicts Mortality: A Computed Tomography Study of 239 Patients. Jung B, Nougaret S, Chanques G, Mercier G, Cisse M, Aufort S, Gallix B, Annane D, Jaber S. Anesthesiology. 2011 Aug;115(2):334-343. (IF :5,35)
• Multimodal nutritional rehabilitation improves clinical outcomes of malnourished patients with chronic respiratory failure: a randomised controlled trial. Pison CM, Cano NJ, Chérion C, Caron F, Court-Fortune I, Antonini MT, Gonzalez-Bermejo J, Meziane L, Molano LC, Janssens JP, Costes F, Wuyam B, Similowski T, Melloni B, Hayot M, Augustin J, Tardif C, Lejeune H, Roth H, Pichard C; the IRAD Investigators(……including M Hayot, C Préfaut). Thorax. 2011 Nov;66(11):953-960.  (IF : 7.04)
• Substrate recognition by the POTRA domains of TpsB transporter FhaC. Delattre AS, Saint N, Clantin B, Willery E, Lippens G, Locht C, Villeret V, Jacob-Dubuisson F. Mol Microbiol. 2011 Jul;81(1):99-112. (IF : 5.60)
• RyRCa Leak Limits Cardiac Ca Window Current Overcoming the Tonic Effect of Calmodulinin Mice. Fernández-Velasco M, Ruiz-Hurtado G, Rueda A, Neco P, Mercado-Morales M, Delgado C, Napolitano C, Priori SG, Richard S, Maríagómez A, Benitah JP. PLoS One. 2011;6(6):e20863. (IF : 4,38)
• What are the specific computed tomography scan criteria that can predict or exclude the need for renal angioembolization after high-grade renal trauma in a conservative management strategy? Charbit J, Manzanera J, Millet I, Roustan JP, Chardon P, Taourel P, Capdevila X. J Trauma. 2011 May;70(5):1219-128. (IF =2.76).
• Is static magnetic field exposure a new model of metabolic alteration? Comparison with Zucker rats. Elferchichi M, Mercier J, Bourret A, Gross R, Lajoix AD, Belguith H, Abdelmelek H, Sakly M, Lambert K. Int J Radiat Biol. 2011 May;87(5):483-90. (IF : 1,89)
• Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae. Brisson L, Gillet L, Calaghan S, Besson P, Le Guennec JY, Roger S, Gore J. Oncogene. 2011 Apr 28;30(17):2070-6. (IF : 7,13)
• Molecular embryology of the foregut. Faure S, de Santa Barbara P. J Pediatr Gastroenterol Nutr. 2011 May;52 Suppl 1:S2-3., (IF: 2,30).
• Mitochondrial production of reactive oxygen species contributes to the {beta}-adrenergic stimulation of mouse cardiomycytes. Andersson DC, Fauconnier J, Yamada T, Lacampagne A, Zhang SJ, Katz A, Westerblad H. J Physiol. 2011 Apr 1;589(Pt 7):1791-801.(IF: 4.79)
• Enhanced cardiomyocyte Ca2+ cycling precedes terminal AV-block in mitochondrial cardiomyopathy Mterf3 KO mice. Andersson DC, Fauconnier J, Park CB, Zhang SJ, Thireau J, Ivarsson N, Larsson NG, Westerblad H. Antioxid Redox Signal. 2011 Nov 1;15(9):2455-64. (IF: 7.58)
• Expression of Dystrophins and the Dystrophin-Associated-Protein Complex by Pituicytes in Culture. Bougrid A, Claudepierre T, Picaud S, Ayad G, Mornet D, Dorbani-Mamine L, Rendon A, Darbeida H. Neurochem Res. 2011 Aug;36(8):1407-16. (IF: 2.72)
• BENEFICIAL EFFECTS OF SR33805 IN FAILING MYOCARDIUM. Mou YA, Toth A, Cassan C, Czuriga D, Detombe PP, Papp Z, Lacampagne A, Cazorla O. Cardiovasc Res. 2011 Aug 1;91(3):412-9. (IF: 6,01)
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